IL-2 THERAPY FOR MELANOMA FUNDAMENTALS EXPLAINED

It is very well understood that IL-two is actually a pleiotropic cytokine positioned within the crossroads of T cell activation and regulation. As such, it is vital to engineer an IL-2 molecule that's biased to effector cells bearing the intermediate affinity receptor, which include naïve and memory CD8+ T cells and NK cells, as opposed to Treg ce